Hugo Mauhin, Brevet de technicien supérieur (BTS) student, started this week in the group as an intern for 3 months.
JOB DESCRIPTION (see French project description below)
We are looking for a highly motivated and talented PhD student to work in the Hermans Lab (Laboratory of Nonequilibrium Complex Systems) on out-of-equilibrium supramolecular chemistry. We are located in ISIS, an institute of the University of Strasbourg (ranked no. 17 in Chemistry worldwide). ISIS houses two Nobel prize laureates in Chemistry (1987 and 2013), and is very international (> 50 different nationalities). The Hermans lab is a young research group with currently 6 members (see our website for recent publications). You will be trained in supramolecular chemistry, and be guided intensively by Dr. Thomas Hermans, the group leader.
The applicant will need to apply to a National grant that can fund the entire PhD trajectory of 3 years. See application procedure in French here (http://ed.chimie.unistra.fr/financement-des-theses/contrat-doctoral-de-recherche/). If you don’t speak French, it’s not a problem. Please send us the following documents:
* A full Curriculum Vitae
* A copy of your Bachelor and Master diploma (in case you do not have your Master yet, a document stating you will receive it on a specific date in 2014).
* A list of the grades you obtained during your Bachelor and Master (so far).
* The following form (http://ed.chimie.unistra.fr/fileadmin/upload/DUN/edsc/03_Financement/2014-Contrats_doctoraux/Candidature-Formulaire_2014_English.doc)
We would be happy to assist you with your application. Please contact us as soon as possible (deadline for application is May 15th 2014)! Applications from any country will be considered. In June there will be interview rounds organized by a special board within the University that can in principle be done by Skype, or in Strasbourg (if you live close by). You will have a good chance of obtaining this prestigious grant only if your grades are sufficiently high, and you are able to defend the project (http://typodun2012.unistra.fr/fileadmin/upload/DUN/edsc/03_Financement/2014-Contrats_doctoraux/Sujet_these_2014_PUPILLO).
One of the great challenges in the field of supramolecular chemistry is to obtain molecular assemblies with a well-defined shape and molecular weight . Such mono-disperse structures are more likely to lead to large scale organization, of key importance in materials science and for biological applications. A viable approach is to induce an anti-cooperative assembly mechanism, by for example steric hindrance  or, as we and others have recently shown, by electrostatic repulsion [2,3]. In this project we will try a revolutionary new methodology to control the length of molecular assemblies using thermal gradients. The molecular assemblies will be studied using a range of optical techniques (UV-absorption, fluorescence and circular dichroism).
L’un des grands défis dans le domaine de la chimie supramoléculaire est d’obtenir des assemblages moléculaires avec une forme bien définie . Ces structures mono-dispersées sont meilleures pour l’organisation à grande échelle et sont d’une importance capitale dans la science des matériaux et pour les applications biologiques. Une approche viable est d’induire un mécanisme de montage anti-coopérative, par exemple pour l’encombrement stérique  ou, comme nous l’avons montré récemment, par repulsion électrostatique [2,3]. Dans ce projet, nous allons essayer une méthode révolutionnaire pour contrôler la longueur des assemblages moléculaires en utilisant des gradients thermiques, qui seront étudiés en utilisant une gamme de techniques optiques (UV-absorption, la fluorescence et le dichroïsme circulaire).
1. Stupp, S. I. et al. Supramolecular Materials: Self-Organized Nanostructures. Science 276, 384 –389 (1997).
2. Besenius, P. et al. Controlled Supramolecular Oligomerization of C3-Symmetrical Molecules in Water: The Impact of Hydrophobic Shielding. Chem. Eur. J. 17, 5193–5203 (2011).
3. Schaefer, C. et al. Controlling the Cooperativity in the Supramolecular Polymerization of Ionic Discotic Amphiphiles via Electrostatic Screening. ACS Macro Lett. 1, 830–833 (2012).
We welcome Alessandro Sorrenti (postdoc), Sicen Liu (Master 1 student), and Nathan Fuchs (Master 1 student) to the group (all started on March 24th 2014)!
Congratulations to Prof. Martin Karplus of ISIS!!
“for the development of multiscale models for complex chemical systems”.
In this perspective you’ll get an idea of what our lab will be working on in the next years: “pushing supramolecular systems out of equilibrium”.
Welcome to Akihiro Sato, who started on May 1st in the lab!
We welcome Vincent Marichez, who started as a master student in the lab. He will be working on magnetophoresis of supramolecular complexes.
Postdoctoral position in the Hermans Lab. We are looking for a highly motivated postdoctoral fellow (> 4 years research experience & PhD degree) with a background in: physical chemistry // organic and/or supramolecular chemistry // physics (or related disciplines). You will be working in the emerging field of non-equilibrium supramolecular chemistry, where we push supramolecular assemblies out of equilibrium by using e.g. shear flows, thermal gradients or concentration gradients. There is little existing equipment to study these non-equilibrium structures and you will therefore have to develop / build (using e.g. photolithography) new instrumentation to 1) create non-equilibrium conditions and 2) study the resulting structures in situ. You will not do synthesis as we obtain molecules through one of our collaborations. Proficiency in the English language is required. Knowledge of UV, Fluorescence and CD spectroscopy and/or light scattering is desirable. Affinity with reaction-diffusion modeling and/or thermodynamics would be great, but is not required. Please send your CV and reference letters to the email address provide here (click here).
The lab will start on March 1st 2013 and will be located on the 1st floor of ISIS (Institut de Science et d’Ingénierie Supramoléculaires). We will start recruiting undergraduate / master / graduate students & postdocs soon. Keep an eye on this site!